Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359504 | 0.90 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL11363855 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL11364062 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL10809677 | 0.80 | MEN1 (0.50) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL7327312 | 0.80 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL30520180 | 0.80 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL6479457 | 0.80 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL7348790 | 0.80 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL5020108 | 0.80 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL6479462 | 0.80 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264497-A | ANTICHOLINERGIC, ANTISPASMODIC, ANTIULCER AND ANTISECRETORY AGENTS | MARUKO SEIYAKU CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |