Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 11/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361695 | 0.91 | TBK1 (0.60) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL11358711 | 0.89 | TBK1 (0.49) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL2906858 | 0.88 | TBK1 (0.59) | TBK1RAB9ANPC1IKBKEKDM4E | |
| SCHEMBL19204349 | 0.86 | TBK1 (0.79) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL11354810 | 0.86 | RAB9A (0.60) | TBK1RAB9ANPC1RXFP1CA12 | |
| SCHEMBL11108156 | 0.84 | MAOB (0.56) | TBK1RAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11356293 | 0.83 | MAOB (0.54) | TBK1RAB9ANPC1RXFP1CA12 | |
| SCHEMBL11358113 | 0.82 | TBK1 (0.53) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL10823671 | 0.80 | RAB9A (0.58) | TBK1RAB9ANPC1RXFP1CA12 | |
| SCHEMBL19196856 | 0.80 | TBK1 (0.82) | TBK1RAB9ANPC1RXFP1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | claimed |