Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865842 | 0.80 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL16567657 | 0.80 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL5865834 | 0.80 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL30559175 | 0.80 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL15352903 | 0.77 | UGT2B7 (0.63) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL434216 | 0.76 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL30033673 | 0.76 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL600527 | 0.76 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL23149900 | 0.74 | SRD5A2 (0.50) | TSHR | |
| SCHEMBL4698142 | 0.74 | UGT2B7 (0.55) | UGT2B7MEN1KMT2AATMSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276305-A | INSECTICIDES, MITICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0014455-A2 | Cyclopropane(thiol)carboxylic-acid esters, processes for their preparation, pesticides containing such compounds and the use of such compounds as pesticides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-08-20 | — | — | EP | disclosed |