Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16567657 | 1.00 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL30559175 | 1.00 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL5865842 | 0.88 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL10333976 | 0.81 | ESR1 (0.45) | UGT2B7CYP1A2TSHRHIF1ACYP3A4 | |
| SCHEMBL11358484 | 0.80 | UGT2B7 (0.57) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL14405124 | 0.79 | UGT2B7 (0.50) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL10333407 | 0.79 | ABCB11 (0.51) | GABBR2GABBR1CYP1A2TSHR | |
| SCHEMBL306953 | 0.78 | ABCB11 (0.54) | GABBR2GABBR1CYP1A2TSHR | |
| SCHEMBL29415272 | 0.77 | CYP2D6 (0.50) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL2849998 | 0.77 | CYP2D6 (0.50) | UGT2B7MEN1KMT2AATMSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087789-B2 | Methods for nucleophilic fluoromethylation | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-08-08 | — | — | US | claimed |
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | SOUTHERN CALIFORNIA, UNIVERSITY OF | 2004-11-18 | — | — | US | claimed |
| WO-2004063129-A2 | METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-07-29 | — | — | WO | claimed |
| US-9359277-B2 | Compositions and processes of preparing and using the same | PURDUE RESEARCH FOUNDATION (US) | 2016-06-07 | — | — | US | disclosed |
| US-9359277-B2 | Compositions and processes of preparing and using the same | PURDUE RESEARCH FOUNDATION (US) | 2016-06-07 | — | — | US | disclosed |
| US-20140039182-A1 | COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME | PURDUE RESEARCH FOUNDATION | 2014-02-06 | — | — | US | disclosed |
| US-20140039182-A1 | COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME | PURDUE RESEARCH FOUNDATION | 2014-02-06 | — | — | US | disclosed |
| US-7087789-B2 | Methods for nucleophilic fluoromethylation | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-08-08 | — | — | US | disclosed |
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | SOUTHERN CALIFORNIA, UNIVERSITY OF | 2004-11-18 | — | — | US | disclosed |
| WO-2004063129-A2 | METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | PHF2, HAO2, GSTM2 | UGT2B7 3885/4885MEN1 4364/4885KMT2A 1266/4885 |
| US-20140039182-A1 | COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME | DBF4, FAU, DHX29 | UGT2B7 1362/4885MEN1 174/4885KMT2A 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.