Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350784 | 0.80 | RIPK1 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6AOC3 | |
| SCHEMBL5865842 | 0.78 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL703634 | 0.77 | AOC3 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6AOC3 | |
| SCHEMBL11358484 | 0.74 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL30559175 | 0.74 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5865834 | 0.74 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL16567657 | 0.74 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL11988223 | 0.74 | CYP2D6 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL1548351 | 0.73 | AOC3 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6AOC3 | |
| SCHEMBL4609324 | 0.72 | KDM4E (0.58) | UGT2B7SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346988-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDRO- BENZOFURAN COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2008-11-12 | — | — | EP | disclosed |
| US-7420070-B2 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKODA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-02 | — | — | US | disclosed |
| US-20050171184-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | AOKI ISAO (JP) | 2005-08-04 | — | — | US | disclosed |
| US-6878831-B2 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20040077712-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1346988-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDRO- BENZOFURAN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171184-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | ALDH1A2, DHPS, DHODH | UGT2B7 910/4885SLC6A2 3578/4885SLC6A4 3758/4885 |
| US-20040077712-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | ALDH1A2, PARK7, DHPS | UGT2B7 850/4885SLC6A2 3520/4885SLC6A4 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.