Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | WNT3A | P56704 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16467017 | 0.83 | KMT2A (0.44) | MTNR1AMTNR1BCTNNB1KDM4EMEN1 | |
| SCHEMBL5218968 | 0.78 | MTNR1A (0.54) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL5405021 | 0.76 | MTNR1A (0.52) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL13202088 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL9312497 | 0.75 | KMT2A (0.59) | CTNNB1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL20978627 | 0.74 | MTNR1A (0.60) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL15967624 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BCTNNB1WNT3AHDAC3 | |
| SCHEMBL15994016 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BCTNNB1WNT3AHDAC3 | |
| SCHEMBL22141048 | 0.74 | KMT2A (0.50) | CTNNB1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL13534264 | 0.74 | MTNR1A (0.64) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248788-A | INTERMEDIATES TO CINNAMOYLPIPERAZINES AND -HOMOPIPERAZINES | DELALANDE S.A. (FR) | 1981-02-03 | — | — | US | disclosed |