SCHEMBL11358982

SCHEMBL11358982

COCc1cc(OP(O)(O)=S)nc(COC)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11354560 0.85
SCHEMBL11366951 0.83
SCHEMBL11358977 0.82 PKM (0.33) PKMALDH1A1TDP1KDM4EHPGD
SCHEMBL11356859 0.76 ALDH1A1 (0.33) ALDH1A1TDP1HSD17B10
SCHEMBL11363283 0.76 ALDH1A1 (0.32) ALDH1A1TDP1HSD17B10
SCHEMBL4271005 0.75 PKM (0.43) PKMALDH1A1TDP1KDM4EHPGD
SCHEMBL10854178 0.75 MEN1 (0.37) ALDH1A1TDP1HSD17B10
SCHEMBL11354555 0.74 PKM (0.32) PKMALDH1A1TDP1KDM4EHPGD
SCHEMBL11366950 0.72 PKM (0.31) PKM
SCHEMBL10854789 0.72 ALDH1A1 (0.44) ALDH1A1TDP1KDM4EHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4308258-A Pyrimidin-4-yl-phosphorus esters and insecticidal, acaricidal or nematocidal compositions and methods using them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-29 US claimed
US-4308258-A Pyrimidin-4-yl-phosphorus esters and insecticidal, acaricidal or nematocidal compositions and methods using them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-29 US disclosed