SCHEMBL4271005

SCHEMBL4271005

COCc1cc(COC)nc(COC)n1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.43
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 6/20 0.40
HPGD P15428 3/20 0.40
HSD17B10 Q99714 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 2/20 0.36
BLM P54132 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
RAB9A P51151 1/20 0.35
S1PR4 O95977 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11355247 0.85 PKM (0.38) PKMALDH1A1KDM4EHPGDHSD17B10
SCHEMBL4595410 0.78 NOS3 (0.32)
SCHEMBL11358982 0.75 PKM (0.32) PKMALDH1A1KDM4EHPGDHSD17B10
SCHEMBL17194884 0.75 HTT (0.43) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL4272782 0.75 PKM (0.43) PKMALDH1A1KDM4EHPGDHSD17B10
SCHEMBL11365668 0.73 HCAR2 (0.33) PKMKDM4E
SCHEMBL4595225 0.73 LMNA (0.43) ALDH1A1KDM4EHPGDTDP1L3MBTL1
SCHEMBL3878733 0.73 S1PR4 (0.33) PKMALDH1A1KDM4EHPGDTDP1
SCHEMBL2117301 0.73 PRKCE (0.38) PKMALDH1A1KDM4EHPGDTDP1
SCHEMBL4594865 0.73 NOS3 (0.32) ALDH1A1TDP1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed