SCHEMBL1135915

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136343	0.88	FFAR4 (0.40)	FFAR4NPC1RAB9AMETFFAR1
	SCHEMBL1136059	0.87	MET (0.40)	FFAR4BRD4METKDM1AKDR
	SCHEMBL2492033	0.87	MET (0.41)	FFAR4NPC1RAB9ASCN8ASCN10A
	SCHEMBL1136119	0.86	MAOB (0.40)	NPC1RAB9AMETKDRAXL
	SCHEMBL1136191	0.83	MET (0.38)	FFAR4BRD4METPARP15PARP10
	SCHEMBL2586505	0.83	FFAR1 (0.41)	FFAR4NPC1RAB9AFFAR1PPARD
	SCHEMBL1136118	0.83	FFAR4 (0.40)	FFAR4NPC1RAB9AMETFFAR1
	SCHEMBL1136267	0.83	FFAR1 (0.40)	FFAR4NPC1RAB9AMETFFAR1
	SCHEMBL1136266	0.82	MET (0.38)	NPC1RAB9AMETKDRAXL
	SCHEMBL1136230	0.82	MGAM (0.40)	NPC1RAB9AMETKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.