SCHEMBL2492033

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136343	0.92	FFAR4 (0.40)	METNPC1RAB9APRKAB2PRKAG1
	SCHEMBL1136119	0.90	MAOB (0.40)	METNPC1RAB9APRKAB2PRKAG1
	SCHEMBL2588182	0.90	FFAR4 (0.52)	METNPC1RAB9AFFAR1FFAR4
	SCHEMBL2586505	0.90	FFAR1 (0.41)	NPC1RAB9AFFAR1FFAR4MAPT
	SCHEMBL1136230	0.89	MGAM (0.40)	METNPC1RAB9ACDK2MAOB
	SCHEMBL2493104	0.89	MET (0.41)	METNPC1RAB9APRKAB2PRKAG1
	SCHEMBL2586698	0.88	FFAR4 (0.42)	METNPC1RAB9AFFAR1FFAR4
	SCHEMBL1136118	0.87	FFAR4 (0.40)	METNPC1RAB9APRKAA1CDK2
	SCHEMBL1136267	0.87	FFAR1 (0.40)	METNPC1RAB9AFFAR1FFAR4
	SCHEMBL2588042	0.87	TSHR (0.39)	METNPC1RAB9AFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.