SCHEMBL1135955

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136193	0.81	HCAR3 (0.64)	ATMTDP1HCAR3MAPTALDH1A1
	SCHEMBL1136123	0.80	ATM (0.47)	ATMTDP1HCAR3MAPTALDH1A1
	SCHEMBL4732740	0.78	KMT2A (0.55)	ATMTDP1HCAR3MAPTALDH1A1
	SCHEMBL1135887	0.77	HCAR3 (0.47)	ATMTDP1HCAR3MAPTALDH1A1
	SCHEMBL21624300	0.77	MAPT (0.61)	MAPTMEN1POLBKMT2ALMNA
	SCHEMBL2840431	0.73	SLC6A2 (0.36)	ALDH1A1KMT2A
	SCHEMBL12898487	0.73	ATM (0.46)	ATMTDP1HCAR3MAPTALDH1A1
	SCHEMBL10019199	0.72	TDP1 (0.49)	ATMTDP1MAPTALDH1A1HTT
	SCHEMBL6512614	0.72	TDP1 (0.45)	ATMTDP1HCAR3MAPTALDH1A1
	SCHEMBL2176406	0.71	HCAR3 (0.47)	HCAR3MAPTALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.