Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.44 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.44 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478388 | 0.86 | PARP10 (0.39) | PARP10NPC1RAB9AKMT2APARP2 | |
| SCHEMBL11347014 | 0.85 | SMN1; SMN2 (0.39) | NPC1RAB9AKMT2APARP2PARP15 | |
| SCHEMBL11472425 | 0.84 | NPC1 (0.43) | NPC1RAB9AKMT2AKDM4EPOLB | |
| SCHEMBL11409809 | 0.84 | TDP1 (0.36) | NPC1RAB9AKMT2AKDM4EPKM | |
| SCHEMBL11489038 | 0.84 | PARP15 (0.41) | PARP10NPC1RAB9AKMT2APARP2 | |
| SCHEMBL11481401 | 0.84 | MCL1 (0.40) | PARP10NPC1RAB9AKMT2APARP2 | |
| SCHEMBL11351095 | 0.84 | TP53 (0.48) | PARP10RAB9AKMT2APARP2PARP15 | |
| SCHEMBL11346661 | 0.82 | PDE11A (0.53) | NPC1RAB9AKMT2AKDM4EPOLB | |
| SCHEMBL11359829 | 0.81 | PARP10 (0.44) | PARP10NPC1RAB9AKMT2APARP2 | |
| SCHEMBL11356753 | 0.81 | PDE1B (0.44) | NPC1RAB9AKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232024-A | ANTIALLERGENS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-04 | — | — | US | claimed |
| EP-0005154-B1 | 1-OXO-1H-PYRIMIDO (6,1-B) BENZOTHIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0005154-A1 | 1-Oxo-1H-pyrimido (6,1-b) benzothiazole derivatives, processes for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-11-14 | — | — | EP | disclosed |