Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359826 | 0.84 | PARP10 (0.47) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL11352930 | 0.83 | LCK (0.36) | KDM4EKMT2AMEN1HPGDMAPT | |
| SCHEMBL11478388 | 0.80 | PARP10 (0.39) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL11347014 | 0.79 | SMN1; SMN2 (0.39) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL11351095 | 0.79 | TP53 (0.48) | RAB9AKDM4EALDH1A1TDP1GAA | |
| SCHEMBL11363546 | 0.79 | KDM4E (0.41) | RAB9AKDM4EALDH1A1TDP1GAA | |
| SCHEMBL11489038 | 0.79 | PARP15 (0.41) | NPC1RAB9AKDM4EGAAPKM | |
| SCHEMBL11481401 | 0.79 | MCL1 (0.40) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL11356753 | 0.78 | PDE1B (0.44) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL11352768 | 0.77 | GABRP (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232024-A | ANTIALLERGENS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-04 | — | — | US | claimed |
| US-4232024-A | ANTIALLERGENS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-04 | — | — | US | disclosed |
| EP-0005154-A1 | 1-Oxo-1H-pyrimido (6,1-b) benzothiazole derivatives, processes for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-11-14 | — | — | EP | disclosed |