Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417444 | 0.93 | DGKA (0.52) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL10804075 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL6430114 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL19532024 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL11155522 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL10454969 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL1417378 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL11122471 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL2351728 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 | |
| SCHEMBL1417334 | 0.91 | DGKA (0.55) | ALDH1A1CES1HSD17B10TDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497374-B2 | Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom | CHIROGATE INTERNATIONAL INC. (TW) | 2025-12-16 | — | — | US | claimed |
| US-12221411-B2 | Processes and intermediates for the preparation of carbaprostacyclin analogues | CHIROGATE INTERNATIONAL INC. (TW) | 2025-02-11 | — | — | US | claimed |
| EP-4098651-B1 | PROCESS FOR THE PREPARATION OF BERAPROST OR SIMILAR BENZOPROSTACYCLIN ANALOGUES STARTING FROM 2-(3-BROMO-2-FLUOROPHENYL)-4-HYDROXYCYCLOPENT-2-ENONE OR SIMILAR REACTANTS | CHIROGATE INT INC (TW) | 2024-02-07 | — | — | EP | claimed |
| US-20230416216-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF BENZOPROSTACYCLIN ANALOGUES AND BENZOPROSTACYCLIN ANALOGUES PREPARED THEREFROM | CHIROGATE INTERNATIONAL INC. (TW) | 2023-12-28 | — | — | US | claimed |
| US-20230357119-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | CHIROGATE INTERNATIONAL INC. (TW) | 2023-11-09 | — | — | US | claimed |
| US-20230357118-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | CHIROGATE INTERNATIONAL INC. (TW) | 2023-11-09 | — | — | US | claimed |
| CN-117003630-A | Methods and intermediates for preparing carboprostacyclin analogs | 佳和桂科技股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| US-20230002339-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF BENZOPROSTACYCLIN ANALOGUES AND BENZOPROSTACYCLIN ANALOGUES PREPARED THEREFROM | CHIROGATE INTERNATIONAL INC. (TW) | 2023-01-05 | — | — | US | claimed |
| EP-4098651-A1 | PROCESS FOR THE PREPARATION OF BERAPROST OR SIMILAR BENZOPROSTACYCLIN ANALOGUES STARTING FROM 2-(3-BROMO-2-FLUOROPHENYL)-4-HYDROXYCYCLOPENT-2-ENONE OR SIMILAR REACTANTS | Chirogate International Inc. (TW) | 2022-12-07 | — | — | EP | claimed |
| CN-115433071-A | Methods and intermediates for preparing benzoprostacyclin analogs, and benzoprostacyclin analogs prepared therefrom | 佳和桂科技股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| EP-1811037-A1 | Process for the preparation of optically active cyclopentenones | Chirogate International Inc. (TW) | 2007-07-25 | — | — | EP | claimed |
| US-20070166809-A1 | Processes for the preparations of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. | 2007-07-19 | — | — | US | claimed |
| EP-0560408-B1 | Enantio- and regioselective syntheses of organic compounds using enol esters as irreversible transacylation reagents | SEARLE & CO (US) | 2000-04-05 | — | — | EP | claimed |
| EP-0454463-B1 | Process for producing epoxyalcohols of high optical purity | ARCO CHEM TECH (US) | 1997-08-13 | — | — | EP | claimed |
| EP-0357009-B1 | Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents | SEARLE & CO (US) | 1994-03-02 | — | — | EP | claimed |
| US-5278070-A | Process for producing epoxyalcohols of high optical purity | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-01-11 | — | — | US | claimed |
| EP-0560408-A1 | Enantio- and regioselective syntheses of organic compounds using enol esters as irreversible transacylation reagents | G.D. SEARLE & CO. (US) | 1993-09-15 | — | — | EP | claimed |
| US-5106750-A | Enzymatic resolution of hydroxycyclopentenones using lipase | G. D. SEARLE & CO. (US) | 1992-04-21 | — | — | US | claimed |
| EP-0454463-A2 | Process for producing epoxyalcohols of high optical purity | ARCO Chemical Technology, L.P. (US) | 1991-10-30 | — | — | EP | claimed |
| EP-0357009-A2 | Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents | G.D. Searle & Co. (US) | 1990-03-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357119-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | PTGIS, PTGIR, PTGES | ALDH1A1 1718/4885CES1 557/4885HSD17B10 206/4885 |
| US-20230357118-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | PTGIS, PTGIR, PTGES | ALDH1A1 1718/4885CES1 557/4885HSD17B10 206/4885 |
| US-12221411-B2 | Processes and intermediates for the preparation of carbaprostacyclin analogues | PTGIS, PTGIR, PTGES | ALDH1A1 1718/4885CES1 557/4885HSD17B10 206/4885 |
| US-20230416216-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF BENZOPROSTACYCLIN ANALOGUES AND BENZOPROSTACYCLIN ANALOGUES PREPARED THEREFROM | PTGIS, PTGER1, PTGIR | ALDH1A1 1266/4885CES1 118/4885HSD17B10 491/4885 |
| US-12497374-B2 | Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom | PTGIS, PTGER1, PTGIR | ALDH1A1 1266/4885CES1 118/4885HSD17B10 491/4885 |
| US-20230002339-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF BENZOPROSTACYCLIN ANALOGUES AND BENZOPROSTACYCLIN ANALOGUES PREPARED THEREFROM | PTGIS, PTGIR, PTGES | ALDH1A1 1759/4885CES1 405/4885HSD17B10 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.