Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351899 | 0.83 | ALDH1A1 (0.41) | ALOX5KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27833841 | 0.75 | KMT2A (0.38) | ALOX5KMT2AALDH1A1LMNACYP2D6 | |
| SCHEMBL2935480 | 0.72 | NPSR1 (0.50) | KMT2AALDH1A1SMN1; SMN2TP53NPSR1 | |
| SCHEMBL28427246 | 0.72 | NPSR1 (0.48) | KMT2AALDH1A1SMN1; SMN2NPSR1GLA | |
| SCHEMBL11299784 | 0.72 | ALDH1A1 (0.41) | ALOX5KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11272720 | 0.68 | POLB (0.45) | KMT2AALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL4654046 | 0.67 | NPSR1 (0.43) | KMT2AALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL1959777 | 0.67 | TSHR (0.46) | ALOX5KMT2ALMNACYP2D6SRC | |
| SCHEMBL30295822 | 0.67 | CYP3A4 (0.43) | ALOX5KMT2AALDH1A1LMNACYP2D6 | |
| SCHEMBL6953010 | 0.66 | CYP2D6 (0.46) | ALOX5ALDH1A1LMNASMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008177-B1 | VULCANIZABLE RUBBER COMPOSITIONS CONTAINING SUBSTITUTED CARBAMIC ACID ESTERS | MONSANTO COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0008177-A1 | Vulcanizable rubber compositions containing substituted carbamic acid esters | MONSANTO COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4156680-A | Scorch inhibited vulcanizable rubber compositions containing carbamic acid esters | MONSANTO COMPANY (US) | 1979-05-29 | — | — | US | disclosed |