Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351899 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNATP53NPSR1 | |
| SCHEMBL10351366 | 0.88 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2LMNATP53NPSR1 | |
| SCHEMBL11272720 | 0.83 | POLB (0.45) | ALDH1A1SMN1; SMN2LMNATP53NPSR1 | |
| SCHEMBL10351504 | 0.79 | NPSR1 (0.39) | ALDH1A1SMN1; SMN2LMNATP53NPSR1 | |
| SCHEMBL11249879 | 0.72 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNATP53NPSR1 | |
| SCHEMBL11364191 | 0.72 | ALOX5 (0.40) | ALDH1A1SMN1; SMN2LMNATP53NPSR1 | |
| SCHEMBL11297916 | 0.71 | NPSR1 (0.43) | ALDH1A1SMN1; SMN2LMNANPSR1GLA | |
| SCHEMBL4210468 | 0.69 | NPSR1 (0.46) | ALDH1A1SMN1; SMN2NPSR1GLATSHR | |
| SCHEMBL2935480 | 0.68 | NPSR1 (0.50) | ALDH1A1SMN1; SMN2TP53NPSR1GLA | |
| SCHEMBL11298575 | 0.68 | MEN1 (0.37) | ALDH1A1SMN1; SMN2LMNANPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |