Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368069 | 0.91 | MAPT (0.57) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11364832 | 0.89 | MAPT (0.59) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11369430 | 0.88 | MAPT (0.62) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11365363 | 0.86 | MAPT (0.54) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11368074 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL11377938 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL11361458 | 0.78 | POLB (0.40) | MAPTALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL11358886 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL11367809 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL11366836 | 0.78 | ALDH1A1 (0.41) | MAPTALDH1A1POLBGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |