Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369430 | 0.98 | MAPT (0.62) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11365363 | 0.97 | MAPT (0.54) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11364249 | 0.89 | MAPT (0.51) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL9187712 | 0.83 | GSK3A (0.56) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11368069 | 0.81 | MAPT (0.57) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL378458 | 0.76 | MAPT (0.96) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11358737 | 0.76 | ALDH1A1 (0.59) | ALDH1A1POLBGSK3AGSK3BLMNA | |
| SCHEMBL11362160 | 0.74 | ALDH1A1 (0.49) | MAPTALDH1A1GSK3AGSK3BLMNA | |
| SCHEMBL223626 | 0.74 | MAPT (1.00) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL11362307 | 0.74 | ALDH1A1 (0.49) | ALDH1A1GSK3AGSK3BLMNAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |