SCHEMBL1136435

SCHEMBL1136435

O=C(Cl)/C=C/c1cccc([N+](=O)[O-])c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.67
▸ MAOB P27338 1/20 0.67
▸ NFE2L2 Q16236 1/20 0.63
▸ FBP1 P09467 2/20 0.61
▸ VCP P55072 1/20 0.61
▸ CYP19A1 P11511 1/20 0.61
▸ HSP90AA1 P07900 3/20 0.60
▸ MITF O75030 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ HTT P42858 1/20 0.60
▸ ATM Q13315 1/20 0.60
▸ TRPV1 Q8NER1 1/20 0.60
▸ ALDH1A1 P00352 3/20 0.58
▸ ITGB2 P05107 1/20 0.58
▸ ICAM1 P05362 1/20 0.58
▸ ITGAL P20701 1/20 0.58
▸ TGM2 P21980 1/20 0.58
▸ GAA P10253 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29626671 1.00 MAPT (0.67) MAPTMAOBNFE2L2FBP1VCP
SCHEMBL29750518 1.00 MAPT (0.67) MAPTMAOBNFE2L2FBP1VCP
SCHEMBL1136437 1.00 MAPT (0.67) MAPTMAOBNFE2L2FBP1VCP
SCHEMBL2744313 0.87 MAPT (0.70) MAPTMAOBNFE2L2FBP1VCP
SCHEMBL2744320 0.87 MAPT (0.70) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL426380 0.85 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL3290556 0.85 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL4179178 0.85 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL29626695 0.85 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL448381 0.85 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116515280-B Oxygen-isolation luminous plastic and preparation method thereof 北京金博轩科技发展有限公司 2024-07-16 — — CN claimed
CN-117965018-A Preparation method of oxygen-isolation luminous plastic 北京金博轩科技发展有限公司 2024-05-03 — — CN claimed
CN-114478256-B Preparation method of novel curcumin derivative and application of novel curcumin derivative in liver cancer resistance 安徽理工大学环境友好材料与职业健康研究院(芜湖) 2024-02-23 — — CN claimed
CN-116515280-A Oxygen-isolation luminous plastic and preparation method thereof 北京金博轩科技发展有限公司 2023-08-01 — — CN claimed
US-20250304563-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2025-10-02 — — US disclosed
EP-4490152-A1 ACTIVATORS OF EFFECTOR T CELLS Orum Therapeutics Inc. (KR) 2025-01-15 — — EP disclosed
CN-116515280-B Oxygen-isolation luminous plastic and preparation method thereof 北京金博轩科技发展有限公司 2024-07-16 — — CN disclosed
CN-116515280-B Oxygen-isolation luminous plastic and preparation method thereof 北京金博轩科技发展有限公司 2024-07-16 — — CN disclosed
CN-117965018-A Preparation method of oxygen-isolation luminous plastic 北京金博轩科技发展有限公司 2024-05-03 — — CN disclosed
CN-117965018-A Preparation method of oxygen-isolation luminous plastic 北京金博轩科技发展有限公司 2024-05-03 — — CN disclosed
CN-117903096-A Cinnamoyl-substituted unsaturated nitrogen-containing heterocycle-containing oxygen-containing compound, composition, preparation method and application 贵州大学 2024-04-19 — — CN disclosed
US-20240100031-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VIRAL INFECTIONS CONTAINING PIPERLONGUMINE-BASED COMPOUND AS ACTIVE INGREDIENT HUSCION CO., LTD. (KR) 2024-03-28 — — US disclosed
EP-0075629-A1 Imidazole derivatives, their preparation, and their pharmaceutical compositions Sumitomo Chemical Industries Ltd. (JP) 1983-04-06 — — EP disclosed
US-4343813-A ANTIANAPHYLACTIC AGENTS PFIZER INC. (US) 1982-08-10 — — US disclosed
US-4331683-A SENSITIZATION, ANTIALLERGENS PFIZER INC. (US) 1982-05-25 — — US disclosed
EP-0050977-A1 Carboxamide compounds as SRS-A antagonists and a process for producing same PFIZER INC. (US) 1982-05-05 — — EP disclosed
EP-0047119-A1 Carboxamide compounds as SRS-A antagonists, pharmaceutical compositions containing them, processes for the preparation, and intermediates useful therein PFIZER INC. (US) 1982-03-10 — — EP disclosed
US-4296129-A ANTIAASTHMATIC INHIBITOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS PFIZER, INC. (US) 1981-10-20 — — US disclosed
US-4296120-A ANTIANAPHYLACTIC PFIZER INC. (US) 1981-10-20 — — US disclosed
US-4264713-A COMPRISING LIGHT SENSITIVE POLYMERS OF AN UNSATURATED POLYESTER AND AN ACRYLIC POLYMER WITH UNSATURATED SIDE CHAINS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304563-A1 ACTIVATORS OF EFFECTOR T CELLS CBLB, CBL, CBLC MAPT 3494/4885MAOB 969/4885NFE2L2 3561/4885
US-20240100031-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VIRAL INFECTIONS CONTAINING PIPERLONGUMINE-BASED COMPOUND AS ACTIVE INGREDIENT SARS1, ACE2, CUL2 MAPT 1922/4885MAOB 3383/4885NFE2L2 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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