3-Nitro-Cinnamic Acid

3-Nitro-Cinnamic Acid

SCHEMBL448381

O=C(O)C=Cc1cccc([N+](=O)[O-])c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.73
MAOB P27338 1/20 0.73
NFE2L2 Q16236 1/20 0.70
FBP1 P09467 1/20 0.63
VCP P55072 1/20 0.63
CYP19A1 P11511 1/20 0.63
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
HSP90AA1 P07900 3/20 0.62
MITF O75030 1/20 0.62
LMNA P02545 1/20 0.62
HTT P42858 1/20 0.62
ATM Q13315 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.61
TRPM8 Q7Z2W7 1/20 0.60
ITGB2 P05107 1/20 0.59
ICAM1 P05362 1/20 0.59
ITGAL P20701 1/20 0.59
TGM2 P21980 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Nitro-Cinnamic Acid SCHEMBL426380 1.00 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL3290556 1.00 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL29626695 1.00 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL4179178 1.00 MAPT (0.73) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL7990710 0.98 MAPT (0.71) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL27877632 0.98 MAPT (0.71) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL7401665 0.98 MAPT (0.71) MAPTMAOBNFE2L2FBP1VCP
3-Nitro-Cinnamic Acid SCHEMBL7990708 0.97 MAPT (0.69) MAPTMAOBNFE2L2FBP1VCP
SCHEMBL5209312 0.91 MAPT (0.62) MAPTMAOBNFE2L2FBP1VCP
SCHEMBL5209309 0.91 MAPT (0.62) MAPTMAOBNFE2L2FBP1VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118754842-A Tryptophan derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2024-10-11 CN claimed
CN-115029849-B Multifunctional warm-keeping knitted fabric and preparation method thereof 泉州禾伦织造有限公司 2024-04-16 CN claimed
CN-114478256-B Preparation method of novel curcumin derivative and application of novel curcumin derivative in liver cancer resistance 安徽理工大学环境友好材料与职业健康研究院(芜湖) 2024-02-23 CN claimed
CN-114014905-B Glycyrrhetinic acid derivative targeting PPARgamma as well as preparation method and application thereof 浙江科技学院 2023-07-21 CN claimed
CN-115537194-A Ligand modified quantum dot, quantum dot film, preparation method of quantum dot film and light-emitting device TCL科技集团股份有限公司 2022-12-30 CN claimed
CN-115029849-A Multifunctional warm-keeping knitted fabric and preparation method thereof 泉州禾伦织造有限公司 2022-09-09 CN claimed
CN-113024573-A Epodophyllotoxin derivative, preparation method and application thereof in preparation of antitumor drugs 江苏百奥信康医药科技有限公司 2021-06-25 CN claimed
US-20190256459-A1 NOVEL PROCESS FOR THE PREPARATION OF BELINOSTAT BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2019-08-22 US claimed
WO-2017199264-A1 NOVEL PROCESS FOR THE PREPARATION OF BELINOSTAT BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2017-11-23 WO claimed
EP-1526584-B1 Method of forming electroluminescent semiconducting nanocrystal patterned layer for an organic-inorganic hybrid electroluminescent devices, and organic-inorganic hybrid electroluminescent device using the same. SAMSUNG ELECTRONICS CO LTD (KR) 2017-06-14 EP claimed
US-20050161666-A1 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-07-28 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1526584-A2 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same Samsung Electronics Co., Ltd (KR) 2005-04-27 EP claimed
US-20050080260-A1 Preparation of prodrugs for selective drug delivery LUMINIDE 2005-04-14 US claimed
US-5830999-A CARBOXYLIC LIGANDS, HEXAMERS REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-11-03 US claimed
US-5376503-A A photo-crosslinkable blends consisting of an isoolefin, a para-alkylstyrene and a photoinitiator substituted on the alkyl group of para-alkylstyrene monomers; corrosion, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US claimed
EP-0563271-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
EP-0563251-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
WO-1992011322-A2 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
WO-1992011295-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080260-A1 Preparation of prodrugs for selective drug delivery APEH, PAH, ALAD MAPT 2279/4885MAOB 70/4885NFE2L2 1468/4885
US-20190256459-A1 NOVEL PROCESS FOR THE PREPARATION OF BELINOSTAT ACR, AADAC, CDK11A MAPT 3904/4885MAOB 3164/4885NFE2L2 4402/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 MAPT 539/4885MAOB 1285/4885NFE2L2 3435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.