Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540445 | 0.82 | KMT2A (0.42) | TYK2ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL11367097 | 0.82 | ALDH1A1 (0.42) | ATMJAK2JAK1TYK2ALDH1A1 | |
| SCHEMBL11079112 | 0.79 | MEN1 (0.46) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL11849641 | 0.73 | HPGD (0.41) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11542709 | 0.73 | KMT2A (0.39) | TYK2KMT2AMAPT | |
| SCHEMBL11363392 | 0.72 | EPHX1 (0.47) | ALDH1A1KMT2AEPHX1POLBMEN1 | |
| SCHEMBL3264512 | 0.72 | ALDH1A1 (0.40) | ATMALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11881288 | 0.70 | GAA (0.37) | ATMJAK2JAK1TYK2ALDH1A1 | |
| SCHEMBL30132112 | 0.66 | FSCN1 (0.48) | ALDH1A1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL10441682 | 0.64 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4290971-A | HYPOTENSIVE AGENTS | DSO "PHARMACHIM" (BG) | 1981-09-22 | — | — | US | disclosed |