Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542709 | 0.90 | KMT2A (0.39) | KMT2ATP53MAPTTYK2GAA | |
| SCHEMBL11364508 | 0.82 | ATM (0.36) | KMT2AALDH1A1MAPTTYK2POLB | |
| SCHEMBL11541965 | 0.81 | AKR1C4 (0.36) | ALDH1A1TSHR | |
| SCHEMBL11541466 | 0.81 | TSHR (0.38) | KMT2AALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL11542282 | 0.80 | ALDH1A1 (0.38) | KMT2AALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL11542649 | 0.80 | MAPT (0.41) | KMT2AALDH1A1MAPTPOLBTSHR | |
| SCHEMBL11514546 | 0.79 | NPC1 (0.34) | KMT2AALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL11367097 | 0.78 | ALDH1A1 (0.42) | KMT2AALDH1A1TYK2POLBTSHR | |
| SCHEMBL11513960 | 0.76 | GABRA1 (0.41) | KMT2ATP53ALDH1A1TSHRMEN1 | |
| SCHEMBL11849641 | 0.76 | HPGD (0.41) | KMT2ATP53ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |