SCHEMBL11366117

SCHEMBL11366117

NC(=O)c1ccccc1N1C=NCC1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.53
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
METAP2 P50579 1/20 0.37
PARP1 P09874 3/20 0.36
BCAT2 O15382 1/20 0.36
TRPA1 O75762 1/20 0.35
SCN9A Q15858 1/20 0.35
IKBKB O14920 1/20 0.35
CDC7 O00311 1/20 0.35
CDK9 P50750 1/20 0.35
RPS6KB1 P23443 2/20 0.34
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8441014 0.85 ALDH1A1 (0.47) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL7673716 0.74 GAA (0.43) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL30577791 0.72 NPC1 (0.46) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL31565663 0.70 NPC1 (0.96) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL3654065 0.70 NPC1 (0.96) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL17009548 0.70 NPC1 (0.89) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL605593 0.69 NPC1 (1.00) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL3083169 0.69 NPC1 (1.00) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL30618181 0.69 NPC1 (0.46) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL10686376 0.69 KDM4C (0.40) KDM4EALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4221586-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1980-09-09 US claimed
US-4297126-A SUPPRESSION OF FLOWERS ON TOBACCO PLANTS AMERICAN CYANAMID CO. (US) 1981-10-27 US disclosed
US-4297126-A SUPPRESSION OF FLOWERS ON TOBACCO PLANTS AMERICAN CYANAMID CO. (US) 1981-10-27 US disclosed
US-4297126-A SUPPRESSION OF FLOWERS ON TOBACCO PLANTS AMERICAN CYANAMID CO. (US) 1981-10-27 US disclosed
US-4221586-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1980-09-09 US disclosed
US-4221586-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1980-09-09 US disclosed
US-4221586-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1980-09-09 US disclosed
US-4201565-A Imidazolinyl benzamides as plant growth regulants AMERICAN CYANAMID COMPANY (US) 1980-05-06 US disclosed
US-4201565-A Imidazolinyl benzamides as plant growth regulants AMERICAN CYANAMID COMPANY (US) 1980-05-06 US disclosed
US-4201565-A Imidazolinyl benzamides as plant growth regulants AMERICAN CYANAMID COMPANY (US) 1980-05-06 US disclosed
US-4122275-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1978-10-24 US disclosed
US-4122275-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1978-10-24 US disclosed
US-4122275-A Imidazolinyl benzamides as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1978-10-24 US disclosed