SCHEMBL10686376

SCHEMBL10686376

O=C(O)c1cnccc1N1C=NCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 12/20 0.40
KDM6B O15054 4/20 0.40
KDM4D Q6B0I6 3/20 0.40
KDM4E B2RXH2 2/20 0.40
KDM4A O75164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
F10 P00742 2/20 0.33
SLC22A12 Q96S37 1/20 0.33
MYC P01106 1/20 0.33
SIRT3 Q9NTG7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8441014 0.80 ALDH1A1 (0.47) KDM4ETDP1MEN1ALDH1A1MAPT
SCHEMBL9412970 0.73 KDM5B (0.30)
SCHEMBL398926 0.71 KDM4C (0.41) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL8696589 0.71 CA12 (0.49) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL4907976 0.71 SMN1; SMN2 (0.50) KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL19480956 0.70 KDM4C (0.47) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL10648416 0.70 KDM4E (0.43) KDM4CKDM6BKDM4DKDM4EKDM4A
Potassium SCHEMBL30402396 0.70 SMN1; SMN2 (0.49) KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL9247305 0.70 MYC (0.51) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL7208486 0.70 KMT2A (0.52) KDM4CKDM6BKDM4DKDM4EKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023202364-A1 HERBICIDAL COMPOSITION COMPRISING PYRIMIDINE FORMYL OXIME DERIVATIVE AND USE THEREOF 青岛清原作物科学有限公司 2023-10-26 WO disclosed
US-4752324-A Certain 2-(5-hydrocarbyl or aryl-1-alkyl-pyrazol-3-yl)-nicotinic acid derivatives having herbicidal activity BAYER AKTIENGESELLSCHAFT (DE) 1988-06-21 US disclosed