Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369085 | 0.94 | PTGS2 (0.55) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11376850 | 0.88 | TTR (0.53) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11372410 | 0.87 | TTR (0.46) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11377095 | 0.87 | RAB9A (0.49) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL14445015 | 0.86 | PTGS2 (0.50) | TTRCYP2C9USP2LMNATBXA2R | |
| Eltenac SCHEMBL145080 | 0.85 | PTGS2 (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11348348 | 0.83 | PTGS2 (0.50) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11376343 | 0.83 | TTR (0.56) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11406525 | 0.83 | TTR (0.50) | TTRCYP2C9USP2LMNATBXA2R | |
| Eltenac SCHEMBL11368803 | 0.82 | PTGS2 (0.68) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |