Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.67 |
| ▸ | TTR | P02766 | 3/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.67 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.67 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.67 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.67 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.67 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.67 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.67 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eltenac SCHEMBL11368899 | 0.92 | PTGS2 (0.58) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL8956861 | 0.92 | PTGS2 (0.72) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| Eltenac SCHEMBL11377896 | 0.90 | PTGS2 (0.55) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL14445015 | 0.87 | PTGS2 (0.50) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL11348348 | 0.87 | PTGS2 (0.50) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| Eltenac SCHEMBL11368803 | 0.86 | PTGS2 (0.68) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL11347865 | 0.86 | CXCL8 (0.55) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL11346658 | 0.85 | PTGS2 (0.59) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL11346220 | 0.85 | CXCL8 (0.70) | PTGS2TTRPTGS1CXCL8ABCB11 | |
| SCHEMBL11366136 | 0.85 | TTR (0.50) | PTGS2TTRPTGS1CXCL8ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 846 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752201-B1 | SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF | UNIV FRIEDRICH ALEXANDER ER (DE) | 2023-11-22 | — | — | EP | claimed |
| EP-3998932-A1 | ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS | Parsons, C. Lowell (US) | 2022-05-25 | — | — | EP | claimed |
| WO-2021011566-A1 | ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS | PARSONS C LOWELL (US) | 2021-01-21 | — | — | WO | claimed |
| EP-3752201-A1 | SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-12-23 | — | — | EP | claimed |
| EP-3609483-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | Urigen Pharmaceuticals, Inc. (US) | 2020-02-19 | — | — | EP | claimed |
| WO-2019158509-A1 | SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-08-22 | — | — | WO | claimed |
| WO-2018191412-A9 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. (US) | 2019-05-31 | — | — | WO | claimed |
| WO-2018191412-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | claimed |
| US-9180249-B2 | Method and device | BIMEDA RESEARCH & DEVELOPMENT LIMITED (IE) | 2015-11-10 | — | — | US | claimed |
| US-9161927-B2 | Drug combinations containing PDE4 inhibitors and NSAIDs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-20 | — | — | US | claimed |
| US-20050171506-A1 | Method and device | ZOETIS BROOMHILL IP LIMITED (IE) | 2005-08-04 | — | — | US | claimed |
| US-6858223-B2 | Compositions comprising phenylaminothiophenacetic acid derivatives for the treatment of acute or adult respiratory distress syndrome (ARDS) and infant respiratory distress syndrome (IRDS) | ALTANA PHARMA AG (DE) | 2005-02-22 | — | — | US | claimed |
| US-20040242597-A1 | Combination | NYCOMED GMBH (DE) | 2004-12-02 | — | — | US | claimed |
| WO-2004071391-A2 | IMIDAZOPYRIDINES CONTAINING COMBINATIONS AND THEIR USE IN TREATING GASTROINTESTINAL INFLAMMATORY DISORDERS | ALTANA PHARMA AG (DE) | 2004-08-26 | — | — | WO | claimed |
| EP-1429807-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA Pharma AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| WO-2003024489-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | claimed |
| EP-1098645-B1 | COMPOSITIONS COMPRISING PHENYLAMINOTHIOPHENACETIC ACID DERIVATIVES FOR THE TREATMENT OF ACUTE OR ADULT RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFANT RESPIRATORY DISTRESS SYNDROME (IRDS) | ALTANA PHARMA AG (DE) | 2002-11-20 | — | — | EP | claimed |
| EP-0005559-B1 | PHENYLAMINOTHIOPHENE ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-11-04 | — | — | EP | claimed |
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | claimed |