Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398156 | 0.88 | PPARA (0.55) | PPARAPDK1ACP1SCDKMT2A | |
| SCHEMBL11393160 | 0.88 | PPARA (0.72) | PPARAKMT2AMEN1MAPTNPC1 | |
| SCHEMBL11398625 | 0.86 | PPARA (0.61) | PPARASCDMAPTLMNA | |
| SCHEMBL11368015 | 0.83 | PPARA (0.65) | PPARASCDKMT2AMEN1MAPT | |
| SCHEMBL11368265 | 0.82 | PPARA (0.82) | PPARAACP1MAPTNPC1 | |
| SCHEMBL7322651 | 0.81 | PPARA (0.72) | PPARAPDK1KMT2AMEN1MAPT | |
| SCHEMBL2844427 | 0.80 | PPARA (0.62) | PPARAACP1KMT2AMEN1MAPT | |
| SCHEMBL11392794 | 0.79 | PPARA (0.67) | PPARAKMT2AMEN1MAPTNPC1 | |
| SCHEMBL11407040 | 0.79 | PPARA (0.70) | PPARAKMT2AMEN1MAPTNPC1 | |
| SCHEMBL11394315 | 0.79 | PPARA (0.70) | PPARAKMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294839-A | Benzothiazole derivatives and pharmaceutical formulations containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-10-13 | — | — | US | disclosed |
| EP-0030632-A2 | Benzothiazole derivatives, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-06-24 | — | — | EP | disclosed |