Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.65 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368265 | 0.86 | PPARA (0.82) | PPARAMAPTDYRK1ANPC1 | |
| SCHEMBL7322651 | 0.85 | PPARA (0.72) | PPARAMAPTMEN1NPC1KMT2A | |
| SCHEMBL11395961 | 0.85 | PPARA (0.49) | PPARAMAOBMAPTSNCAMEN1 | |
| SCHEMBL11387996 | 0.83 | MAOB (0.51) | PPARAMAOBMAPTSNCASCD | |
| SCHEMBL11366252 | 0.83 | PPARA (0.60) | PPARAMAPTSCDMEN1NPC1 | |
| SCHEMBL7324620 | 0.82 | PDK1 (0.60) | PPARAMAPTDYRK1AMEN1NPC1 | |
| SCHEMBL11393160 | 0.80 | PPARA (0.72) | PPARAMAPTMEN1NPC1KMT2A | |
| SCHEMBL11398625 | 0.79 | PPARA (0.61) | PPARAMAPTSCD | |
| SCHEMBL7331187 | 0.79 | PPARA (1.00) | PPARAMAPTMEN1NPC1KMT2A | |
| SCHEMBL11370453 | 0.79 | PPARA (0.74) | PPARADYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294839-A | Benzothiazole derivatives and pharmaceutical formulations containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-10-13 | — | — | US | disclosed |
| EP-0030632-A2 | Benzothiazole derivatives, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-06-24 | — | — | EP | disclosed |