Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11869804 | 0.76 | POLB (0.59) | MAOBPOLBMEN1PTPN1KMT2A | |
| SCHEMBL28569270 | 0.76 | POLB (0.62) | POLBMEN1PTPN1KMT2AALDH1A1 | |
| SCHEMBL31037935 | 0.76 | POLB (0.62) | POLBMEN1PTPN1KMT2AALDH1A1 | |
| SCHEMBL1253672 | 0.75 | MAOB (1.00) | MAOBADORA2B | |
| SCHEMBL30059662 | 0.75 | MAOB (1.00) | MAOBADORA2B | |
| SCHEMBL10994834 | 0.74 | ALOX15 (0.59) | MAOBPOLBMEN1KMT2AGAA | |
| SCHEMBL11872015 | 0.73 | PTPN1 (1.00) | MAOBPOLBMEN1PTPN1KMT2A | |
| SCHEMBL29950744 | 0.73 | PTPN1 (1.00) | MAOBPOLBMEN1PTPN1KMT2A | |
| SCHEMBL11485184 | 0.73 | ALDH1A1 (0.55) | MAOBPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL21591554 | 0.72 | POLB (0.57) | MAOBPOLBMEN1PTPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159268-A | ANTIBIOTICS, MICROBIOCIDES | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |