Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734513 | 0.94 | CYSLTR2 (0.42) | TSHRCYSLTR2CYSLTR1TAAR1LIPG | |
| SCHEMBL1263570 | 0.91 | NOS2 (0.42) | TSHRCYSLTR2CYSLTR1TAAR1NOS2 | |
| SCHEMBL7169105 | 0.88 | LIPG (0.48) | CYSLTR2CYSLTR1LIPGALOX5PTGS2 | |
| SCHEMBL11066029 | 0.88 | GABRA1 (0.41) | TSHRCYSLTR2CYSLTR1TAAR1LIPG | |
| SCHEMBL28355115 | 0.87 | LIPG (0.42) | CYSLTR2CYSLTR1LIPGALOX5PTGS2 | |
| SCHEMBL9839949 | 0.87 | NOS2 (0.42) | TSHRCYSLTR2CYSLTR1TAAR1NOS2 | |
| SCHEMBL9046397 | 0.86 | TAAR1 (0.34) | TSHRCYSLTR2CYSLTR1TAAR1LIPG | |
| SCHEMBL18260105 | 0.86 | LIPG (0.52) | CYSLTR2CYSLTR1LIPGALOX5PTGS2 | |
| SCHEMBL7769446 | 0.86 | LIPG (0.52) | CYSLTR2CYSLTR1LIPGALOX5PTGS2 | |
| SCHEMBL8932620 | 0.86 | LIPG (0.52) | CYSLTR2CYSLTR1LIPGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503648-A | Styryl Pyrazolopyrimidines, pharmaceutical composition and preparation method and purposes | 安徽医科大学 | 2018-09-07 | — | — | CN | disclosed |
| US-4297508-A | BY REACTING CARBON DIOXIDE WITH B-NAPHTHOL, AN ALKALI METAL SALT OF B-NAPHTHOL, AND AN ALKYLBENZENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-27 | — | — | US | disclosed |