Nitrogen

Nitrogen

SCHEMBL11366394

COc1ccc(OC)c(Cl)c1.N#N

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 1/20 0.50
SLC6A4 P31645 2/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CYP1A1 P04798 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP1B1 Q16678 2/20 0.45
CYP3A4 P08684 1/20 0.45
HTR2A P28223 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197088 0.96 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL29587997 0.96 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL6002589 0.93 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL22059520 0.81 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL1047487 0.81 CA12 (0.45) CA12CA1CA2CA7CA9
Nitrogen SCHEMBL8497790 0.81 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2092408 0.81 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL12603887 0.79 TAS1R3 (0.49) CA12CA1CA2CA7CA9
SCHEMBL5862483 0.79 HTR2A (0.54) SLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL177471 0.79 CA12 (0.43) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4287228-A ARYLDIAZONIUM SALTS AMERICAN CAN COMPANY (US) 1981-09-01 US claimed
US-4287228-A ARYLDIAZONIUM SALTS AMERICAN CAN COMPANY (US) 1981-09-01 US disclosed
US-4287228-A ARYLDIAZONIUM SALTS AMERICAN CAN COMPANY (US) 1981-09-01 US disclosed