SCHEMBL5862483

SCHEMBL5862483

COc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 18/20 0.54
SLC6A4 P31645 18/20 0.54
KCNH2 Q12809 16/20 0.54
HSP90AA1 P07900 1/20 0.53
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMO O15229 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24749733 0.85 ALDH1A1 (0.59) HTR2ASLC6A4KCNH2HSP90AA1
SCHEMBL31694884 0.85 ALDH1A1 (0.59) HTR2ASLC6A4KCNH2HSP90AA1
SCHEMBL10269448 0.85 AR (0.54) HTR2ASLC6A4KCNH2
SCHEMBL11175966 0.83 HSP90AA1 (0.57) HTR2ASLC6A4KCNH2HSP90AA1SLC6A2
SCHEMBL31287771 0.83 HSP90AA1 (0.57) HTR2ASLC6A4KCNH2HSP90AA1SLC6A2
SCHEMBL5540628 0.83 SLC6A4 (0.40) HTR2ASLC6A4KCNH2HSP90AA1SLC6A2
SCHEMBL197088 0.83 CA12 (0.62) HTR2ASLC6A4SLC6A2SLC6A3
SCHEMBL29587997 0.83 CA12 (0.62) HTR2ASLC6A4SLC6A2SLC6A3
SCHEMBL17791828 0.83 BACE1 (0.47) KMO
SCHEMBL21820786 0.82 HSP90AA1 (0.71) HTR2ASLC6A4KCNH2HSP90AA1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7038021-B2 Anti-dioxins monoclonal antibody suitable for assaying dioxins in environment and hybridoma producing the same KYOTO ELECTRONICS MANUFACTURING CO., LTD. (JP) 2006-05-02 US disclosed
US-20050153378-A1 Anti-dioxins monoclonal antibody suitable for assaying dioxins in environment and hybridoma producing the same KYOTO ELECTRONICS MANUFACTURING CO., LTD. (JP) 2005-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050153378-A1 Anti-dioxins monoclonal antibody suitable for assaying dioxins in environment and hybridoma producing the same DDT, CD2, TEAD4 HTR2A 2719/4885SLC6A4 3567/4885KCNH2 1294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.