SCHEMBL197088

SCHEMBL197088

COc1ccc(OC)c(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
ALDH1A1 P00352 4/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
THRB P10828 1/20 0.54
KMT2A Q03164 1/20 0.54
SLC6A4 P31645 2/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
CYP1A1 P04798 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP1B1 Q16678 2/20 0.48
CYP3A4 P08684 1/20 0.48
HTR2A P28223 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29587997 1.00 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL6002589 0.98 CA12 (0.60) CA12CA1CA2CA7CA9
Nitrogen SCHEMBL11366394 0.96 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL1047487 0.85 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL2092408 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL22059520 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL12603887 0.83 TAS1R3 (0.49) CA12CA1CA2CA7CA9
SCHEMBL5862483 0.83 HTR2A (0.54) SLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL177471 0.83 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL13019819 0.83 CA12 (0.48) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112028748-B Preparation method of 2, 5-dimethoxychlorobenzene 百合花集团股份有限公司 2022-09-23 CN claimed
CN-212539351-U Floating ball liquid level meter for rectifying 4-chloro-2, 5-dimethoxybenzene 大名县名鼎化工有限责任公司 2021-02-12 CN claimed
CN-112028748-A Preparation method of 2, 5-dimethoxychlorobenzene 百合花集团股份有限公司 2020-12-04 CN claimed
CN-111960947-A Method for synthesizing 4-chloro-2, 5-dimethoxy nitrobenzene by using microreactor 百合花集团股份有限公司 2020-11-20 CN claimed
CN-101510622-B Electrolyte for lithium ion secondary battery and battery containing the electrolyte BYD CO LTD 2012-07-04 CN claimed
CN-101510622-A Electrolyte for lithium ion secondary battery and battery containing the electrolyte BYD CO LTD (CN) 2009-08-19 CN claimed
EP-1832568-A1 Method for manufacturing chlor-1,4-dimethoxybenzene Saltigo GmbH (DE) 2007-09-12 EP claimed
US-4285863-A YELLOW-TO-RED ORGANIC PIGMENTS; PLASTICS AND FABRICS; PAINTS, ENAMELS, AND INKS MONTEDISON S.P.A. (IT) 1981-08-25 US claimed
JP-58144486-A None JP disclosed
JP-56133480-A None JP disclosed
US-20250066309-A1 DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS ROCHE PALO ALTO LLC (US) 2025-02-27 US disclosed
US-20250025462-A1 METHODS OF USING DIAMINOPYRIMIDINE P2X3 AND P2X2/3 RECEPTOR MODULATORS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISEASES ROCHE PALO ALTO LLC (US) 2025-01-23 US disclosed
CN-118344856-A Foam completion fluid and preparation method thereof 中国石油化工股份有限公司石油勘探开发研究院 2024-07-16 CN disclosed
CN-118325591-A Plugging drilling fluid and preparation method thereof 中国石油化工股份有限公司石油勘探开发研究院 2024-07-12 CN disclosed
US-4285863-A YELLOW-TO-RED ORGANIC PIGMENTS; PLASTICS AND FABRICS; PAINTS, ENAMELS, AND INKS MONTEDISON S.P.A. (IT) 1981-08-25 US disclosed
US-4125622-A ANTITHROMBOSIS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-11-14 US disclosed
US-4082809-A P-BENZOQUINONE DIKETALS HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed
US-4066708-A PROCESS FOR PREPARING CHLORINATED HYDROQUINONE DIMETHYL ETHERS HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4057586-A Process for the manufacture of hydroquinone dimethyl ethers HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-08 US disclosed
US-4046652-A Process for preparing p-benzoquinone diketals HOECHST AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066309-A1 DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS P2RX3, P2RX6, P2RX2 CA12 4606/4885CA1 2902/4885CA2 1106/4885
US-20250025462-A1 METHODS OF USING DIAMINOPYRIMIDINE P2X3 AND P2X2/3 RECEPTOR MODULATORS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISEASES P2RX3, P2RX2, P2RX1 CA12 3683/4885CA1 3217/4885CA2 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.