Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.65 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246180 | 0.84 | GRIN2B (0.67) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 | |
| Fenharmane SCHEMBL9695673 | 0.79 | GRIN2B (1.00) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 | |
| SCHEMBL9700846 | 0.79 | KDM4E (0.48) | GRIN2BMAPKAPK2HTR7CYP3A4 | |
| Hydrochloric Acid SCHEMBL9701609 | 0.78 | KDM4E (0.48) | GRIN2BMAPKAPK2HTR7CYP3A4 | |
| Fenharmane SCHEMBL9696484 | 0.78 | GRIN2B (0.97) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18087743 | 0.77 | GRIN2B (0.76) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 | |
| SCHEMBL5532807 | 0.76 | GRIN2B (0.70) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 | |
| SCHEMBL8321835 | 0.76 | KMT2A (0.70) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11249624 | 0.75 | KMT2A (0.72) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 | |
| SCHEMBL29264061 | 0.74 | MAPKAPK2 (0.72) | GRIN2BMAPKAPK2HTR7CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277476-A | ANTI-ANOXIA AND PSYCHOTROPIC AGENTS | SYNTHELABO (FR) | 1981-07-07 | — | — | US | disclosed |