Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9701609 | 0.99 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1LMNAGRIN2B | |
| SCHEMBL2269874 | 0.80 | GRIN2B (0.60) | GRIN2BCYP3A4MAPKAPK2HTR7 | |
| SCHEMBL11366451 | 0.79 | GRIN2B (0.65) | GRIN2BCYP3A4MAPKAPK2HTR7 | |
| SCHEMBL3246180 | 0.74 | GRIN2B (0.67) | GRIN2BCYP3A4MAPKAPK2HTR7 | |
| SCHEMBL7894771 | 0.70 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1LMNAPARP1 | |
| SCHEMBL5532807 | 0.69 | GRIN2B (0.70) | GRIN2BCYP3A4MAPKAPK2HTR7 | |
| SCHEMBL8321835 | 0.69 | KMT2A (0.70) | KDM4EHSD17B10ALDH1A1GRIN2BCYP3A4 | |
| SCHEMBL10690885 | 0.68 | LMNA (0.52) | KDM4EALDH1A1LMNASTAT3MEN1 | |
| Hydrochloric Acid SCHEMBL11249624 | 0.68 | KMT2A (0.72) | KDM4EHSD17B10ALDH1A1GRIN2BCYP3A4 | |
| SCHEMBL13598000 | 0.68 | KDM4E (0.88) | KDM4EHSD17B10ALDH1A1LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014465-A1 | USE OF ANNULATED TETRAHYDROPYRIDINACETIC ACID DERIVATES FOR TREATING NEUROLOGICAL DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-03 | — | — | WO | disclosed |