Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352715 | 0.81 | MAPKAPK2 (0.55) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL30363189 | 0.80 | MAPKAPK2 (0.56) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL30363250 | 0.80 | MAPKAPK2 (0.56) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL30363161 | 0.79 | MAPKAPK2 (0.55) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL30363083 | 0.79 | MAPKAPK2 (0.55) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL8039623 | 0.78 | SIRT1 (0.56) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL8041738 | 0.76 | MAPKAPK2 (0.54) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL6237350 | 0.75 | MAPKAPK2 (0.55) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL6238434 | 0.74 | MAPT (0.55) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 | |
| SCHEMBL6358856 | 0.74 | MAPKAPK2 (0.54) | MAPKAPK2KCNH2SIGMAR1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277476-A | ANTI-ANOXIA AND PSYCHOTROPIC AGENTS | SYNTHELABO (FR) | 1981-07-07 | — | — | US | disclosed |