Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767061 | 0.76 | RXRB (0.41) | MCL1LMNASMN1; SMN2RXRARXRB | |
| SCHEMBL2099150 | 0.74 | BCL2L1 (0.38) | MCL1LMNASMN1; SMN2RXRARXRB | |
| SCHEMBL11357112 | 0.74 | BCL2L1 (0.38) | NR1D1MCL1LMNASMN1; SMN2RXRA | |
| SCHEMBL11355027 | 0.73 | BCL2L1 (0.48) | LMNASMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL9720039 | 0.72 | BCL2L1 (0.54) | LMNASMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL6003271 | 0.71 | BCL2L1 (0.38) | MTNR1AMTNR1BMCL1LMNASMN1; SMN2 | |
| SCHEMBL2091729 | 0.71 | LMNA (0.40) | NR1D1MCL1LMNASMN1; SMN2RXRA | |
| SCHEMBL3887208 | 0.70 | RXRB (0.45) | MCL1LMNASMN1; SMN2RXRARXRB | |
| SCHEMBL28514277 | 0.70 | LMNA (0.60) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2486276 | 0.70 | DRD2 (0.48) | MTNR1AMTNR1BTBXA2RS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276305-A | INSECTICIDES, MITICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |