SCHEMBL6003271

SCHEMBL6003271

[CH2]COCCCCc1cccc2c1CCCC2

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
HTR1A P08908 1/20 0.34
SLC6A4 P31645 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
TBXA2R P21731 1/20 0.33
RXRA P19793 4/20 0.33
RXRB P28702 4/20 0.33
RXRG P48443 4/20 0.33
MCL1 Q07820 2/20 0.32
DHFR P00374 2/20 0.32
DPP4 P27487 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CXCR2 P25025 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093920 0.89 BCL2L1 (0.36) BCL2L1BADHTR1ASLC6A4SMN1; SMN2
SCHEMBL2099150 0.85 BCL2L1 (0.38) BCL2L1BADHTR1ASLC6A4SMN1; SMN2
SCHEMBL2091729 0.82 LMNA (0.40) BCL2L1BADHTR1ASLC6A4SMN1; SMN2
SCHEMBL6368014 0.81 BCL2L1 (0.44) BCL2L1BADSMN1; SMN2LMNATBXA2R
SCHEMBL2094732 0.81 LMNA (0.41) BCL2L1BADHTR1ASLC6A4SMN1; SMN2
SCHEMBL9115008 0.78 BCL2L1 (0.38) BCL2L1BADSMN1; SMN2LMNATBXA2R
SCHEMBL9720039 0.77 BCL2L1 (0.54) BCL2L1BADSMN1; SMN2LMNATBXA2R
SCHEMBL6542314 0.76 MEN1 (0.43) BCL2L1BADLMNATBXA2RMCL1
SCHEMBL6542272 0.75 ALDH1A1 (0.46) BCL2L1BADSLC6A4LMNAMCL1
SCHEMBL11355027 0.74 BCL2L1 (0.48) BCL2L1BADSMN1; SMN2LMNATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 WO disclosed