Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HK1 | P19367 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350388 | 0.83 | KDM4E (0.44) | KDM4EKMT2AMAPTMEN1GAA | |
| SCHEMBL29065067 | 0.77 | POLB (0.42) | KDM4EKMT2AMAPTMEN1GAA | |
| SCHEMBL11361948 | 0.76 | CNR2 (0.49) | KDM4EMAPTALDH1A1HK1SMN1; SMN2 | |
| SCHEMBL922975 | 0.76 | MAOB (0.51) | KDM4EKMT2AMAPTMEN1GAA | |
| SCHEMBL11354910 | 0.73 | ALDH1A1 (0.46) | KDM4EMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL25392488 | 0.72 | MEN1 (0.38) | KDM4EKMT2AMAPTMEN1RECQL | |
| SCHEMBL25393644 | 0.72 | MEN1 (0.38) | KDM4EKMT2AMAPTMEN1RECQL | |
| SCHEMBL25392489 | 0.72 | MEN1 (0.38) | KDM4EKMT2AMAPTMEN1RECQL | |
| SCHEMBL13448507 | 0.70 | GRM2 (0.43) | KDM4EGAAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25393045 | 0.70 | ALDH1A1 (0.33) | KDM4EKMT2AMAPTMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256759-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |