SCHEMBL25392489

SCHEMBL25392489

CC(CC#N)Cn1cccc1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ POLB P06746 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC7 Q8WUI4 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ HDAC9 Q9UKV0 1/20 0.33
▸ HDAC5 Q9UQL6 1/20 0.33
▸ EPHX2 P34913 5/20 0.32
▸ PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25392488 1.00 MEN1 (0.38) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25393644 1.00 MEN1 (0.38) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25299545 0.84 MEN1 (0.36) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25299544 0.84 MEN1 (0.36) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25393045 0.83 ALDH1A1 (0.33) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25392180 0.82 MEN1 (0.33) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25392772 0.82 MEN1 (0.33) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25392182 0.82 MEN1 (0.33) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL29065067 0.79 POLB (0.42) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL25395261 0.76 KDM4E (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230286973-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2023-09-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286973-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G MEN1 1348/4885KMT2A 4825/4885ALDH1A1 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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