Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354910 | 0.81 | ALDH1A1 (0.46) | TDP1ALDH1A1LMNAMAPTCYP2D6 | |
| SCHEMBL25392488 | 0.79 | MEN1 (0.38) | POLBAPEX1TDP1L3MBTL1MEN1 | |
| SCHEMBL25393644 | 0.79 | MEN1 (0.38) | POLBAPEX1TDP1L3MBTL1MEN1 | |
| SCHEMBL25392489 | 0.79 | MEN1 (0.38) | POLBAPEX1TDP1L3MBTL1MEN1 | |
| SCHEMBL29229 | 0.79 | LMNA (0.44) | POLBAPEX1TDP1L3MBTL1MEN1 | |
| SCHEMBL31328905 | 0.78 | PKM (0.48) | POLBAPEX1TDP1L3MBTL1MEN1 | |
| SCHEMBL11367101 | 0.77 | KDM4E (0.38) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL29030310 | 0.77 | EPHX2 (0.43) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10503892 | 0.76 | KDM4E (0.36) | POLBTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL20894093 | 0.76 | LMNA (0.42) | POLBAPEX1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |