Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375936 | 0.81 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL1763254 | 0.81 | — | — | |
| SCHEMBL17727009 | 0.76 | USP2 (0.34) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL9836459 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL11510340 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL9175656 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7817837 | 0.73 | — | — | |
| SCHEMBL687799 | 0.73 | — | — | |
| Bromide SCHEMBL11220167 | 0.69 | DYRK3 (0.32) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL9888758 | 0.69 | LMNA (0.39) | MEN1KMT2ASMN1; SMN2MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251262-A | 1-Carbamoyl-1,2,4-triazole herbicidal agents | THE BOOTS COMPANY LIMITED (GB) | 1981-02-17 | — | — | US | disclosed |