SCHEMBL9836459

SCHEMBL9836459

CCCCCCSc1nc[nH]n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
USP2 O75604 1/20 0.43
GPR84 Q9NQS5 2/20 0.43
PAK1 Q13153 1/20 0.43
GAA P10253 2/20 0.42
HTT P42858 2/20 0.42
ALPL P05186 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
TSHR P16473 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTGES O14684 2/20 0.40
XDH P47989 2/20 0.40
HAO1 Q9UJM8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175656 1.00 SMN1; SMN2 (0.50) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL11510340 1.00 SMN1; SMN2 (0.50) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL1763254 0.85
SCHEMBL17727017 0.83 SMN1; SMN2 (0.36) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL11511847 0.83 SMN1; SMN2 (0.37) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL17727034 0.80 ALDH1A1 (0.35) SMN1; SMN2LMNAMAPTALDH1A1HPGD
Bromide SCHEMBL11220167 0.76 DYRK3 (0.32) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL11367182 0.75 MEN1 (0.36) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL11375936 0.74 SMN1; SMN2 (0.38) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL11334284 0.73 SMN1; SMN2 (0.51) SMN1; SMN2LMNAMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2023-06-20 US disclosed
CN-110475782-B Triazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2022-05-17 CN disclosed
EP-3608327-B1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2022-05-04 EP disclosed
EP-3608327-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-02-12 EP disclosed
US-20200031852-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2020-01-30 US disclosed
EP-0157322-B1 PHOTOGRAPHIC RECORDING MATERIAL, PROCESS FOR STABILIZING A PHOTOGRAPHIC RECORDING MATERIAL AND TRIAZOLES Agfa-Gevaert AG (DE) 1991-07-03 EP disclosed
US-4897341-A DEVELOPMENT INHIBITOR RELEASING COUPLER CONTAINING A 3-ALKYLTHIO-1,2,4-TRIAZOLYL GROUP AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1990-01-30 US disclosed
US-4840880-A DEVELOPMENT INHIBITOR RELEASING COMPLEX AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1989-06-20 US disclosed
US-4833070-A Color photographic recording material containing a yellow DIR coupler AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1989-05-23 US disclosed
EP-0157322-A2 Photographic recording material, process for stabilizing a photographic recording material and triazoles Agfa-Gevaert AG (DE) 1985-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof CYP51A1, TLK2, SIK2 SMN1; SMN2 4822/4885LMNA 3218/4885MAPT 2147/4885
US-20200031852-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SEPTIN8, SIK2, CYP51A1 SMN1; SMN2 4784/4885LMNA 3722/4885MAPT 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.