Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836459 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL9175656 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL1763254 | 0.85 | — | — | |
| SCHEMBL17727017 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL11511847 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL17727034 | 0.80 | ALDH1A1 (0.35) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| Bromide SCHEMBL11220167 | 0.76 | DYRK3 (0.32) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL11367182 | 0.75 | MEN1 (0.36) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL11375936 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL11334284 | 0.73 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |