Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353964 | 0.90 | TSHR (0.51) | TSHRL3MBTL1EPHX1KDM4EMEN1 | |
| SCHEMBL11354175 | 0.84 | L3MBTL1 (0.44) | TSHRL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL11363959 | 0.83 | SMN1; SMN2 (0.45) | TSHRL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL28415275 | 0.79 | TSHR (0.54) | TSHRL3MBTL1NPC1HPGDCRHBP | |
| SCHEMBL11365323 | 0.79 | TSHR (0.44) | TSHRL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL11573236 | 0.76 | L3MBTL1 (0.44) | TSHRL3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL10110920 | 0.76 | METAP2 (0.47) | NPC1HPGDRAB9AEPHX1MEN1 | |
| SCHEMBL8403428 | 0.76 | METAP2 (0.47) | NPC1HPGDRAB9AEPHX1MEN1 | |
| SCHEMBL8683270 | 0.75 | F10 (0.44) | TSHRSLC6A2SLC6A3SLC6A4CYP3A4 | |
| SCHEMBL11218340 | 0.73 | LMNA (0.49) | TSHRL3MBTL1HPGDRAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278678-A | ANTILIPEMIC AGENTS | KAKEN CHEMICAL CO., LTD. (JP) | 1981-07-14 | — | — | US | disclosed |