Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365731 | 0.82 | ADRB2 (0.48) | ADRB3ALDH1A1ADRB2ADRB1 | |
| SCHEMBL11366337 | 0.81 | ADRB2 (0.47) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11373565 | 0.75 | ADRB2 (0.46) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11374980 | 0.74 | ADRB2 (0.45) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11367805 | 0.74 | ADRB2 (0.44) | ADRB3ALDH1A1ADRB2ADRB1 | |
| SCHEMBL11369119 | 0.73 | ADRB3 (0.44) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11367476 | 0.73 | ADRB2 (0.42) | ADRB3ALDH1A1SMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL11367776 | 0.73 | MTNR1A (0.48) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11366331 | 0.69 | ADRB2 (0.45) | ADRB3ALDH1A1SMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL11573676 | 0.68 | ADRB2 (0.53) | ADRB3ALDH1A1SMN1; SMN2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304790-A | 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof | SCHERING CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |