Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923474 | 0.75 | BACE1 (0.45) | GAATSHRLMNAPOLBALDH1A1 | |
| SCHEMBL11221046 | 0.74 | GAA (0.44) | GAATSHRLMNACASP3POLB | |
| SCHEMBL19923680 | 0.73 | ELANE (0.56) | LMNAALDH1A1HTR1AHTR6MEN1 | |
| SCHEMBL18106819 | 0.73 | GAA (0.50) | GAATSHRLMNACASP3CYP1A2 | |
| SCHEMBL11790326 | 0.72 | HTR1A (0.43) | GAATSHRLMNAPOLBALDH1A1 | |
| SCHEMBL26948730 | 0.72 | ALDH1A1 (0.57) | GAATSHRLMNACYP2C9POLB | |
| SCHEMBL11365777 | 0.70 | GAA (0.37) | GAATSHRCASP3POLBALDH1A1 | |
| SCHEMBL18106832 | 0.70 | GAA (0.47) | GAATSHRLMNACASP3CYP2C9 | |
| SCHEMBL11372927 | 0.70 | GAA (0.45) | GAATSHRLMNACASP3CYP1A2 | |
| SCHEMBL11795906 | 0.70 | HTR1A (0.41) | LMNAPOLBALDH1A1HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258149-A | AND AN ORGANIC PEROXIDE CATALYST OR RADIATION | CIBA-GEIGY CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4167465-A | Unsaturated hydantoin coagents | CIBA-GEIGY CORPORATION (US) | 1979-09-11 | — | — | US | disclosed |
| US-4091223-A | CROSSLINKERS FOR PVC, POLYETHYLENE, VINYL ACETATE COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |