Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394020 | 0.88 | ALDH1A1 (0.61) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL11911198 | 0.87 | LMNA (0.57) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL11912164 | 0.82 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL13990626 | 0.82 | LMNA (0.53) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL10774897 | 0.81 | LMNA (0.55) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL10520781 | 0.81 | LMNA (0.68) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL30881266 | 0.81 | LMNA (0.68) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL899628 | 0.81 | LMNA (0.68) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL10774901 | 0.81 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL1065677 | 0.81 | LMNA (0.68) | LMNASMN1; SMN2KMT2AGPBAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272438-A | SILYLATING, ACYLATION | GLAXO GROUP LIMITED (GB) | 1981-06-09 | — | — | US | disclosed |