Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368299 | 1.00 | ACE (0.43) | ACEMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL10396256 | 0.85 | MEN1 (0.49) | ACEMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL11404534 | 0.75 | ACE (0.54) | ACEDPP4FAP | |
| SCHEMBL29374265 | 0.74 | DPP7 (0.65) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL2123083 | 0.74 | DPP7 (0.65) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL2123080 | 0.74 | DPP7 (0.65) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL2113409 | 0.74 | DPP7 (0.65) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL2113410 | 0.74 | DPP7 (0.65) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL27796855 | 0.74 | DPP7 (0.65) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL30558183 | 0.74 | MEN1 (0.44) | ACEMEN1TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021883-A2 | N-acyl-amino acid derivatives and pharmaceutical compositions containing them, intermediates and starting compounds | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-01-07 | — | — | EP | disclosed |