SCHEMBL30558183

SCHEMBL30558183

C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP2D6 P10635 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ ACE P12821 1/20 0.42
▸ APLNR P35414 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30558180 0.91 ITGB3 (0.42) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL10396256 0.88 MEN1 (0.49) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL29409428 0.86 OPRK1 (0.49) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL30817477 0.84 ACE (0.49) ACE
SCHEMBL30423512 0.84 ACE (0.49) ACE
SCHEMBL30490568 0.84 ACE (0.43) ACE
SCHEMBL29609766 0.84 ACE (0.51) ACE
SCHEMBL30485831 0.83 ACE (0.43) MAPTACE
SCHEMBL29666810 0.82 ACE (0.43) MAPTACE
SCHEMBL30138997 0.81 ACE (0.42) MAPTACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240041740-A1 SKIN PEEL COMPOSITIONS GLO PHARMA INC (US) 2024-02-08 — — US disclosed
US-20230270635-A1 METHODS AND COMPOSITIONS FOR COSMETIC APPLICATIONS GLO PHARMA INC (US) 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270635-A1 METHODS AND COMPOSITIONS FOR COSMETIC APPLICATIONS CUTA, GLA, LIPA MEN1 1376/4885TP53 763/4885CYP1A2 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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